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Additional insights may be derived by data integration and cross-platform comparisons of expression profiles.
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To determine the functional annotation of protein-coding genes and RNAs, we deployed both a series of automated annotation tools and manual efforts, incorporating a wide variety of research information by data integration, literature curation, and genomic comparison against the relative strains in E. coli.
Sun et al. [19] integrated multi-source genetic data for schizophrenia by a data integration and weighting framework in which the strength of evidence in different data categories is considered and combined by appropriate weights.
We demonstrate how this database can be used effectively for the improvement of functional annotation by employing data integration and clustering.
Srihari et al.[ 14] have analysed complexes in core cellular processes to decipher cancer mechanisms, by data integration at the protein-protein interaction and gene expression levels, across all cancer conditions.
Fig. 4 shows the relationships between bovine ALAS1 and other proteins that were determined by data integration in the STRING 9.0 database.
It's the first major news for Programmable Web since it was acquired by data integration provider Mulesoft earlier this year.
By data integration, one may identify trajectory patterns of particularly exposed human groups.
We detected a prominent platform bias, which however can be overcome by data integration.
The improvement achieved by the combined dataset indicated that more statistical power was gained by data integration.
Overall, Logical models and Empirical models were most commonly used, followed by Extrapolation, Simulation/Process models, Data integration, and Direct mapping.
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