Sentence examples for by covalent modification of from inspiring English sources
However, in the more closely related species Bradyrhizobium japonicum, glyoxylate cycle flux is not controlled by covalent modification of isocitrate dehydrogenase enzyme [23].
Since the side chain group of nerol is not reactive, it is unlikely that inhibition is mediated by covalent modification of TRPV1.
This type of chemical inactivation renders the virus non-infectious by covalent modification of internal virion proteins required for viral replication, whilst preserving the structural and functional integrity of the viral envelope glycoproteins [11], [12], [13].
Many cellular events are dictated by covalent modification of proteins, an important mechanism in regulating protein and genome function; of which protein methylation is an important posttranslational modification with activating or repressive effects.
The correlation between the abnormal shift and the initial mass of the unmodified DUB suggests that the decrease in gel mobility is based on steric properties of the branched adduct, and is not caused by covalent modification of a single DUB by multiple ISG15VS molecules.
SecY268FlEG was made by covalent modification of SecYK268CEG with fluorescein [ 24].
DNA packaging and its influence on gene expression can also occur by covalent modifications of the histone protein core around which DNA is wrapped in the chromatin structure or else by remodeling carried out by chromatin remodeling complexes (see Chromatin remodeling).
The biological activity and cellular distribution of a given protein is often modulated by covalent modifications of amino acid side chains.
This could be brought about by covalent modifications of histone tails that weaken the nucleosome-DNA interaction [31], or by histone remodeling enzymes that disassemble the nucleosomes or displace nucleosomes along the chromatin [32], [33].
Epigenetic regulation of gene expressions is hierarchically regulated by covalent modifications of histone, which preceded methylation of promoter DNA.
Epigenetic changes were mainly materialized by covalent modifications of DNA methylation and protein modifications (methylation, acetylation, phosphorylation).
