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Gene expression was determined by correcting samples for reference gene values (cyclophilin A), and values were expressed relative to the control group per experiment.
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Thus, we suggest dealing with differences in the sample composition by correcting country scores for differences in terms of age and schooling with a mathematical model.
Improving the published formulations by correcting for the effects of sampling resulted in better approximations in areas where the published formulations were weak.
However, we have automatically corrected for this type of bias by correcting for ZIP code by using a posterior matching procedure, as samples from women within the same ZIP code were always analyzed in the same laboratory.
This is performed by correcting for signal concentration with the concentration of 18S signal for each sample (signal conc./18S conc).
Corrected results were calculated by correcting for misclassifications.
This program generated null distributions of the appropriate size (e.g., matching the size of each sample examined here and thus correcting for sample size) by randomly resampling haplotypes (with replacement) from a source population followed by counting haplotypes and calculating haplotype diversity for each replicate.
In this study, we used a more efficient EMMA, eXpedited (EMMAX), which reduces the computational time for analyzing large GWAS data sets and includes PCA eigen vectors and identity by descent (IBD) matrices in correcting for sample structure [ 42, 45].
Correcting for sample selection improves the fitting of the model, adding 14%% extra correct predictions.
The change in fluorescence emission of samples titrated with Pif1 was corrected for sample dilution by subtracting the change in the fluorescence emission of oligonucleotide samples titrated with equal volumes of protein sample buffer.
The amount of polymer retained by the sand was then calculated by difference, after correcting for any sample (Table 3).
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