Sentence examples for by coordinating cell cycle from inspiring English sources

Together, these data support that JNK2 prevents replicative stress by coordinating cell cycle progression and DNA damage repair mechanisms.

It is usually thought that this cell size maintenance is brought about by coordinating cell cycle progression with attainment of a critical size, which will result in cells having a limited size dispersion when they divide.

In addition, through its chromatin-remodeling activity, osa is known to regulate the cell cycle by coordinating cell-cycle progression through downstream genes, such as CycE interaction or string/cdc25 expression, in normal vs. cancer cells (Baig et al. 2010; Brumby et al. 2002; Moshkin et al. 2007).

Other studies identified some of the mechanisms coordinating cell cycle and differentiation decisions in the retina.

CDKs regulate checkpoints that integrate mitogenic and growth inhibitory signals, coordinating cell cycle transitions.

Thus, the majority of genes revealed by the screen may perform conserved functions throughout metazoans as components of the machinery coordinating cell cycles with development.

Wnt signaling can coordinate cell cycle progression by regulating modulators of cell cycle checkpoints [ 31].

KRIT1 negatively coordinates cell cycle also in mouse embryo fibroblasts (MEFs) by controlling FoxO-mediated downregulation of cyclin D1 and upregulation of p27Kip1 levels through the modulation of intracellular ROS levels [22].

Furthermore, DSBs also elicit a checkpoint response, which coordinate cell cycle progression with DNA repair capacity (reviewed in [2] [4]).

Following the phosphorylation of H2AX, repair proteins such as the MRN complex, ATM, and 53BP1 coordinate cell cycle arrest, DNA repair and apoptosis [3].

In addition to their well-established role as microtubule organizers, centrosomes serve as important scaffolds for the integration of multiple signaling pathways that coordinate cell cycle progression [13].