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Most of the drugs introduced into the body by conventional methods, using oral tablets and intravenous injections, encounter problems including poor solubility, undesirable biodistribution, burst release kinetics, tissue damage during extravasation, cytotoxicity, and many more objectionable side effects.
Principal components analysis (PCA) was carried out by conventional methods using the eigen function of Splus or R, starting with (a) the 2,833×2,833 between genes covariance matrix and (b) the 14×14 between samples covariance matrix (13 time points plus the asynchronous control).
Reference antisera were prepared by conventional methods using inactivated viruses [ 26].
The massive undertaking to clone ORFs by the thousands cannot be easily achieved by conventional methods using restriction endonucleases.
The processing of specimens and identification of isolates were performed by conventional methods using the Vitek Yeast Biochemical Card (BioMerieux, Marcy l'Etoile, France) [ 17].
Species identification was centrally performed as previously described and reconfirmed by conventional methods using the API 20NE (Bio Merieux – SA- Marcy l'Etoile – France).
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In fact, by conventional methods, used for EDF fabrication, it is difficult to avoid the formation of Er 3+ ion pairs and the amount of glass modifiers must be maximized to reach the suited optical properties [13].
A sensitive quantitative polymerase chain reaction (QPCR) permits the detection of mRNA in small quantities that could not be detected by conventional methods used to detect proteins.
Within 24 h, the result was confirmed by conventional method using MicroScan (Siemens, West Sacramento, CA, USA) Gram-negative identification panel with 99.9% probability of E. meningosepticum and later by Vitek2 Gram-negative card (bioMerieux).
The XTEM specimen was prepared by a conventional method using mechanical polishing and ion thinning in a Gatan PIPS device.
These were compared to intraoral photographs taken by the conventional method using a single-lens reflex camera and mirror.
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by routine methods using
by enzymatic methods using
by spectrophotometric methods using
by statistical methods using
by immunohistochemical methods using
by conventional methods employing
by traditional methods using
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by stereological methods using
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by conventional architectures using
by colorimetric methods using
by numerical methods using
by molecular methods using
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