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This suggests that GABA might play a key role in regulating adult hippocampal neurogenesis by controlling levels of network activity and the release of morphogens in the vicinity of precursor cells.
Firstly, polyphosphate acts as a regulator of the stringent response by controlling levels of sigma factors and through binding to RNA polymerase, inhibiting transcription of genes involved in exponential growth [19].
Our model proposes regulation of the sphingosine – S1P rheostat by controlling levels of SPPase.
HO-2 is constitutively expressed and also appears as a critical regulator of apoptosis by controlling levels of extracellular superoxide dismutase and apoptotic signaling kinase-1.
We show that TDP-43 and FUS localize in nuclear Gems through association with the SMN complex, and are involved in maintenance of the spliceosome by controlling levels of U snRNAs.
Caspase 6 normally is simply classified as an effector caspase in cell death pathways; but in B cells caspase 6 negatively regulates CD40- and TLR-dependent G1 entry, in part by controlling levels of phosphorylated retinoblastoma (Rb) protein.
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These experiments suggest that stimulation of CXCR4 by its endogenous ligand controls levels of NR2B protein in vivo.
Microsoft tightly controls levels of customisation by handset makers.
In plants, the role of proteasomes is associated with regulation of developmental events by controlling the levels of nuclear regulatory proteins (TF) by the ubiquitin-proteasome system in proliferating and developing tissues [ 31].
Collectively, these results provide molecular evidence that ZEB1 is required for the adipogenic transcriptional program by controlling mRNA levels of a broad range of genes during adipogenesis.
Another recent study has shown that the two RNAse III endonucleases dicer and drosha inhibit the expression of thrombospondin-1 by controlling the levels of let-7 and miR-27b, thus modulating angiogenesis [23].
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by reducing levels of
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