Sentence examples for by controlling activity of from inspiring English sources

Exact(2)

I support this conclusion and propose that Shh signalling regulates retinal expression of p57kip2 by controlling activity of p53.

p21Cip1/WAF1 protects cells against apoptosis through its CDK inhibitory activity, but also by controlling activity of transcription factors such as E2F1, c-Myc or STAT3.

Similar(58)

There have been numerous studies recently that have aimed to develop strategies for reducing on-target/off-tumor toxicity by controlling activity and proliferation of CART cells.

These include the regulation of cell motility and differentiation by controlling the activity of ROK-α and the regulation of apoptosis by suppressing the activity of the proapoptotic kinases ASK1 and MST2, none of which requires Raf-1 kinase activity (reviewed in [ 45- 47]).

Having had relatively little help from us, she fought the insufferable days and the anxiety the only way she knew how: by creating a constant whirlwind of controlling activity.

Our previous data suggested that p57 downregulation accelerated the invasion of HCC cells by controlling the activity of LIMK1 and subsequently reducing the phosphorylation of cofilin [ 11].

A complex set of allosteric feedback loops are thought to allow the four dNTP pools to achieve the desired concentrations and stoichiometry, in large part by controlling the activity of RNR towards each of its substrates.

Phorbol esters, via binding to the PKC C1 domains, cause major effects on mitogenesis by controlling the activity of cyclin cdk complexes and the expression of cdk inhibitors.

In normal cells p16ink4a functions as a negative regulator of cell cycle progression by controlling the activity of tumor suppressor pRb.

CsgD also regulates cellulose synthesis at a post-transcriptional level by controlling the activity of several cellulose synthases including BcsB through the synthesis of c-di-GMP by AdrA.

Scientists knew that REST played a key role in fetal brain development by controlling the activity of certain genes, but they thought it was absent in adult brains.

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