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Contrarily, chronic inflammation is featured by continual activation of the adaptive immune system that exacerbates the inflammatory response.
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Continual activation of leukocyte populations, triggered by unrelenting infections, tissue damage or the anomalous behavior of the mutated cells, contributes to the progression of neoplastic transformation with multiple mechanisms that range from reactive oxygen species to growth and angiogenic factors [ 6].
CTX irreversibly abolishes the GTPase activity of the Gs α subunit, inducing continual activation of adenylyl cyclase and increased intracellular levels of cAMP.
However, a sustained heat shock would give rise to ongoing protein denaturation, leading to continual activation of HSPs.
Interestingly, the colon had constitutively high levels of NT, which may be attributable to continual activation and surveillance of the gut microbial community by resident macrophages and epithelial cells.
A study of patients with systemic sclerosis showed evidence of epigenetic changes in fibroblasts that may contribute to their continual activation [ 43].
The shallow-water, shallow-basin model produces thick evaporites by continual subsidence of the basin floor.
Tumour regression was accompanied by continual improvement of performance status.
Methanol extraction was carried out by continual stirring of the powder in methanol at 25°C for 24 h.
24 25 Analytic rigour was aided by continual re-examination of the data by all authors throughout the research process.
By contrast, activation of layer V/VI pyramidal neurons causes nonspecific network activation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com