Sentence examples for by constructing a genome from inspiring English sources

In this work, we developed a method for identifying the core structure among moderately related microbial genomes by constructing a genome alignment based on the consensus gene order.

It presents a series of models, beginning with the simplest (which is progressively extended by dropping restrictions), each constructing a genome rearrangement problem.

Therefore, we sought to reduce ambiguity in mapping repetitive elements by constructing a reference Mtb H37Rv genome with only a single MIRU copy at each locus.

One of the key characteristics of the aforementioned methods is that, at least in theory, read mapping can be carried out regardless of the availability of a reference genome by constructing a reference sequence from overlapping sequence stacks [ 21, 23- 26].

We can construct a genome space.

However, to take full advantage of the ability to reduce coverage in Sanger-based plastid genome sequencing would require the sequencing of pure plastid DNA, something that can only reliably be achieved at present by constructing whole-genome bacterial artificial chromosome (BAC) libraries and then strictly sequencing plastid DNA-containing clones.

(6) proposed AlleleSeq for constructing a modified diploid genome by inserting SNPs and indels into the reference genome and using this diploid genome as the reference during alignment to avoid errors caused by reference bias.

First, we validate the robustness of previous findings by constructing genome-wide predictive models for different mammalian cell types and modelling algorithms.

Incorporating genomic information into allelic ratio measurements, for example by normalizing allelic RNA expression ratios to matched DNA ratios or by constructing personalized reference genomes for mapping, greatly improves allelic RNA ratio estimates [ 14, 26, 27].

The orthologous group data found by orthoMCL were used to construct a whole-genome phylogenetic tree based on gene content.

CEGMA uses a set of conserved protein families from the Clusters of Orthologous Groups database (Tatusov et al. 2003) to annotate a genome by constructing DNA-protein alignments between the proteins and the assembled scaffolds.