Sentence examples for by considering the binding from inspiring English sources
The sensitivity of a nanosensing approach is dependent on the capacity of nanomaterials to transduce the target binding process to an enhanced detectable signal, while the selectivity is achieved by considering the binding affinity and specificity of recognition elements to their target.
In contrast, our method predicts the binding sites by considering the binding conformations of the query ligand.
Some 30%% of these so-called 'holes in the T-cell repertoire' can be explained by considering the binding stability of the peptide HLA complex [ 46].
However, our recent study showed that by considering the binding peptide inside the HLA-binding groove, the performance of molecular modeling and prediction was improved.
In the previous results, the spatial distribution of the TFBSs for a functional gene cluster as constructed by considering the binding site data of all TFs.
In this study, we choose PDNN as it is more powerful by considering the sequence binding information [ 18, 19].
Previous efforts were made to tackle this task by considering the fact that TF binding sites tend to be more conserved than other functional sites and the binding sites of several TFs are often clustered.
If a more sensible prior is used, for example, by considering the empirical prior from the binding frequencies in the validation data, the proposed method can attain even higher accuracy than the regression method (results not shown).
In addition, Kiselyov et al. proposed a mathematical model that describes the kinetic properties of insulin and insulin-like growth factor 1 receptor binding and activation, by considering the combinatorial complexity arising from multivalent binding to multiple receptor conformations.
By considering the final series of metal binding sites on NikR, we now present a detailed mechanism of action for this metal responsive transcription factor that is consistent with the in vitro biochemical data.
TF binding information was downloaded from MsigDB, which strengthened the prediction of true binding sites by considering the conservation across genomes [ 24].
