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Mouse model of early stage of PBC was constructed by consecutive administration of poly I C.
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One cycle consisted of consecutive administration of S-1 for 28 days followed by a 2-week rest period, and cycles were repeated up to 4 times.
Cui et al. [124] examined PFOS and PFOA excretions in male rats during a 28-day consecutive administration of PFOS and PFOA.
As expected, consecutive administration of GA for 14 days significantly reduced the tumor size and tumor vascularization evidenced by decreased CD31 expression in tumors.
The consecutive administration of MDMA dramatically altered the profile of stress-responsive genes as follows.
CO was assessed by thermodilution with two consecutive administrations of 10 mL of cold saline.
Administration was stopped after the patient indicated at two consecutive administrations of the questionnaire (over at least 24 hours) that she had no activity impairment.
One course consisted of consecutive administration for 28 days followed by 14 days of no drug administration.
Further, hepatic triglyceride (TG) level was also investigated after consecutive administration (13 days) of GCBE and its constituents.
A single course consisted of consecutive administration for 28 days followed by a 2-week rest; administration was repeated over four courses.
The reduction in the number of these genes by consecutive MDMA administration implies the potential for a drug-induced amelioration of the stress response.
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