Sentence examples for by conducting interim analyses from inspiring English sources

Here, average sample sizes are decreased by conducting interim analyses with the possibility to stop the investigation early if the result is significant.

"As it is open-label, we will conduct interim analyses during the study, and can do so at any time," says Editas spokesperson Cristi Barnett.

We did not conduct interim analyses because of insufficient enrolment of patients.

The DSMB met a total of five times and conducted interim analyses of the safety data, pertaining to the occurrence of AE/SAEs.

The trial statistician will conduct interim and final analyses blind to allocation.

An independent Data Safety Monitoring Board comprised of three members with expertise in statistics, critical care and clinical epidemiology conducted two interim analyses.

These estimates are also supported by repeated interim analyses from the German central ONJ register (Felsenberg et al 2006).

RCTs must be closely monitored by independent Steering Committees and Data Safety Monitoring Boards (DSMB) complemented by interim analyses and early stopping rules [5].

Multistage designs involve conducting one or more interim analyses to decide whether all patients planned for a trial should be recruited.

Four unblinded safety evaluations have been conducted, along with two interim analyses.

Projected accrual was 120 cases, but enrollment was stopped at 103 cases in July 2012 on the basis of interim analyses conducted after 5 years.