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Impairment of myocardial function in patients with shock is often masked by concurrent elevations in cardiac index and a low systemic vascular resistance, making parameters such as LVEF often unreliable for monitoring LV systolic function and as a prognostic marker [ 1, 47].
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Elevations in liver enzymes were generally asymptomatic and reversible and concurrent elevations in both ALT and bilirubin were rare.
No patient had concurrent elevations in ALT or AST and bilirubin or alkaline phosphatase.
Others (34– 37) have reported diet-induced increases in plasma apoCIII and concurrent elevations in plasma triglycerides, mainly as a result of increased dietary carbohydrate intake.
Concurrent elevations in ALT and bilirubin levels after pazopanib treatment could indicate liver toxicity (Kaplowitz, 2006); therefore, it is important to rule out this possibility to allow continued treatment.
The concurrent elevation in IGF-1R (both a and b isoforms) transcripts over time during development supports the concept that IGF signaling pathways play a key role during development [17], [18].
Elevated LD levels without concurrent elevation in CK in BALB/c mice and common voles are suggestive of hepatocellular damage.
Elevated lactate dehydrogenase levels (three-fold) with concurrent elevation in creatine kinase (two-fold) in the present study are thus suggestive of skeletal or cardiac muscle damage [ 36].
Based on the data presented above we concluded that BRCA1-IRIS-overexpressing TNBC cells show concurrent elevation in the expression of 'EGFR, AKT, MDM2, Skp2 and survivin'.
31 Although uric acid excretion is initially increased, there appears to be little risk for uric acid nephropathy with losartan because of the concurrent elevation in urine pH resulting from reduced bicarbonate reabsorption.
> -wrap-foot> Elevatinns in aminotransferases ≥3 times the upper limit of normal occurred in 3.2% of patients in the pirfenidone group compared with 0.6% of patients in the placebo group, including one patient in the pirfenidone group with concurrent elevation in serum total bilirubin >2 times the upper limit of normal.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com