Sentence examples for by concurrent activation of from inspiring English sources

When the levels of hepatocellular sterols drop, Srebf2 is activated and this process restores the normal levels by concurrent activation of de novo cholesterol synthesis and increased uptake of plasma cholesterol through Ldlr.

Thus, cortical RG might be susceptible to transformation into ependymoma CSC by concurrent activation of NOTCH signalling and deletion of INK4A/ARF.

PKC activation may also be important for H. pylori-regulation of the tight junction [ 65] as activation of PKC increases TER by reducing phosphorylation of MLC [ 81] and decreased TER in T84 colonic epithelial cells induced by H. pylori was prevented by concurrent activation of PKC using the phorbol ester phorbol 12-myristate 13-acetate (PMA) [ 65].

The correlation between platelets and monocytes may be explained by the concurrent activation of CD147 on the platelet and monocyte populations, especially Mon2 monocytes, by common agonists.

In tumor cells the persistent and prolonged activation of JNK and p38 is made possible because, the initial action of PKC- ζ, is supported by the concurrent activation of PKC- δ.

ICA is a statistical technique that separates the brain signals into independent spatial maps, clustering areas characterised by concurrent activation.

Using the rat skin as a model for cancer induction by ionizing radiation, we found concurrent activation of K-ras and c-myc oncogenes in end-stage tumors.

The concurrent activation of brain stress pathways by cocaine could explain why initially drug-naïve rats were more hesitant in sampling the cocaine-rewarded lever than the saccharin-rewarded lever in the present study.

Continence is achieved during the urine storage phase by inhibition of the parasympathetic nervous system and concurrent activation of the sympathetic nervous system.

There is also a concurrent activation of the anti-viral pathway mediated by type I interferon genes, with up to a ten-fold increase in some of these genes (Fig. S4A).

In most cases, the concurrent activation of STAT-1 and NF-kB pathways by a cytokine mixture is required for the full induction of target genes and consequent severe β-cell damage [ 12– 12].