The time course of the reflected or transmitted light intensity during aggregation is used to assess both the magnitude of RBC aggregation as well as the aggregation kinetics by computing the indexes of aggregation.
The prognostic accuracy of the model was quantified by computing the concordance index (c-index) described by Harrell et al. [ 11].
The discriminatory powers of different typing methods were estimated by computing the numerical index of discrimination, the Hunter-Gaston Discriminatory Index (HGDI), as described previously [ 36].
The source geometry is estimated by computing the structural index from previously determined depth and location.
The fit of the observed pairwise mismatch distributions to a sudden expansion demographic model was tested using a generalized least square procedure and by computing the raggedness index of the observed distributions [ 109] as implemented in ARLEQUIN.
Thus, by computing the Kakwani index for each health financing mechanism, weighting it for the contribution of that financing mechanism in the total and summing them up, one can obtain the overall progressivity of the health system.
Genetic variation was assessed within each mosquito strain by computing the Shannon index of phenotypic diversity S [ 31] with Popgene v1.32 as well as the pair-wise Jaccard coefficients [ 32] with the vegdist function of the vegan R package.
Within each cell, and hence subpopulation, we assumed that the drugs acted independently and examined whether they exhibited synergy at the cell population level by computing the combination index., and indicate synergy, additivity, and antagonism, respectively.
The vulnerability of the network to a given scheme of vertex removal was quantified by computing the V-index, a value complementary to the R-index (R).
The ability of the models to discriminate between participants with and without all-cause mortality was estimated by computing the c-index, a generalization of the c-statistic or the area under the curve, which allows for censored data.
