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The microcontroller, which held analog to digital converter (ADC), was operated by computer programming using advanced virtual RISC (AVR) based on C language (Additional file 1).
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The data were treated by computer program using descriptive and inferential statistics.
The raw minute-by-minute activity counts were then transformed into energy expenditure by the computer program using MET prediction algorithms of Klippel et al [ 32].
Calculations were performed by a computer program using MATLAB (MathWorks, Natick MA, USA) written by one of the authors.
After an eligibility check, the patients will be randomly assigned to receive EPA or placebo at the central registration center by a computer program using a minimization method, with stratification by age, gender, BMI, and institution.
After an eligibility check, the patients will be randomly assigned to receive metformin or placebo at the central registration centre by a computer program, using a minimization method, with stratification by institute, age, gender and BMI.
They were produced by a computer program using a simple algorithm.
The search was done by a computer program using the "simulated annealing" algorithm with a constant time temperature schedule.
The concentration of the dye in the solution was calculated by a computer program using a calibration curve.
The randomization sequence was generated by a computer program using blocks of three to ensure a 2∶1 ratio of vaccine allocation.
Randomization assignments were generated by a computer program using a permuted block design with a variable block size.
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