In the present study, digitized images of histologic sections from laryngeal cancer lesions, immunohistochemically stained for P63 expression, were used to analyze, by computer processing, the amount of P63 staining and the texture of P63 expressed nuclei and relate them to the histologic grade of the lesion.
These techniques entail the acquisition or rendering of a spectrum for each point mapped on the surface of the object (one spectrum per pixel) followed by computer processing of the large data cube to generate maps with contrasts based on the varying signal intensity and thus abundance of the materials being targeted, generally chemical elements or compounds.
The aim of the present study was to analyse by computer processing microscopy images of biopsy material from laryngeal cancer lesions, which had been stained for P63 expression.
Regarding the percentage of P63 expressed nuclei, the particular parameter was calculated for each patient automatically by computer processing of the 4 patient images, and it referred to the percentage of P63 expressed nuclei over the total number of nuclei detected within the areas of interest, which were indicated by the expert physician.
Briefly, the net phosphorus distribution was obtained by computer processing of images collected at different energy loss values according to the three-window method.
The system, which is being being slowly rolled out across the UK and is years behind its original schedule, is also dogged by computer processing errors, poor communications with claimants, and delays in fixing simple administrative problems, says the study by a group of Citizens Advice offices.
A disinterested third person performed the randomization by computer processing with the random number generation program.
Genome profiling (GP) uses a set of DNA fragments sampled from genomic DNAs, and is composed of three fundamental steps: random PCR, micro-temperature gradient gel electrophoresis (μTGGE), and data normalization by computer processing [ 22, 32].
Aided by extensive computer processing power, the genome researchers have been engaged in what is essentially a giant software project.
The maps are produced by complex computer processing, which find the best-fit projected maps for the few pixels of the Hubble images.
