Sentence examples for by computational programs and from inspiring English sources
Here, we investigated the relationship between miRNA activities determined by computational programs and miRNA expression levels by using data in which both mRNA and miRNA expression from the same samples were measured.
We use this characteristic relative z-score of the ncRNA class to predict the ncRNA fraction in putative ncRNAs as determined in the FAN-TOM3 database and by computational programs RNAz and EvoFold.
With the availability of high-throughput assays, novel functional elements – such as enhancers and DNase I hypersensitive sites (DHSs), are being discovered by computational programs at a very rapid pace.
Analysis of exCNVs shows that the number of exCNVs predicted by computational programs differ considerably from each other.
FN CNVs were considered as the CNVs which were detected only by the exaCGH array experiments but not predicted by computational programs.
The predicted MtrH tertiary structure was supported by both computational programs PROQ (Wallner and Elofsson 2003) and ANOLEA (Melo et al. 1997).
The pathogenicity of the SORT1 p.G171A mutation is supported by its absence in neurologically normal population, its prediction as pathogenic by different computational programs, its high conservation across other orthologs), its location in a relevant functional domain), and its effects on both sortilin downregulation–(c)) and p75NTR upregulation).
Each HGT candidate predicted by the three computational programs was subject to further manual phylogenetic analyses.
By using four different computational programs, only two SNVs were predicted to be deleterious by all programs.
For comparison purposes, we also determined the expression of two other genes, IL-10 and bFGF, predicted as targets for miR-140 (bFGF) and miR-27a (IL10); these predictions were also obtained by the same five computational programs as described above.
The usefulness of the modeling and the validity of the computational programs are demonstrated by comparison with experimental results obtained by using a model rotor.
