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Thus, these findings suggest that the elevated fracture risk among diabetics is impacted by complex changes in tissue properties that ultimately reduce the fracture resistance of bone.
In practice, we found in pilot experiments that ZD7288 also influences presynaptic processing as apparent by complex changes in the synaptic currents evoked by the dimmest flashes.
Our findings indicate that ASD is characterised by complex changes in GM developmental trajectories of several brain regions.
Chronic renal disease (CKD) is characterized by complex changes in cell metabolism leading to an increased production of oxygen radicals, that, in turn has been suggested to play a key role in numerous clinical complications of this pathological condition.
Transcriptome plasticity is conferred not only by altering the concentration levels of transcripts, but also by complex changes in the architecture of transcripts (splice isoforms, editing, transcription start and termination sites).
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Thus, alcohol and stress seem to paralyze adaptive innate immune functions by inducing complex changes in NK cells and other adaptive immune signaling that in the brain primarily involves microglial astrocyte neuronal HMGB1 TLR signaling.
Analysis of specific mRNA levels by RT-PCR demonstrated complex changes in both menisci following ACL transection (Hellio Le Graverand et al., 2001d).
Interestingly, thermal annealing followed by addition of CaCl2 caused complex changes in the observed agent relaxivity (Table 1 ).
A strength of this method isthat, by numerically computing the locations of a few key curves in phase space, we canobtain information about model trajectories generated by arbitrary initial conditionsand determine how complex changes in stable firing patterns occur as parameters arevaried.
But the centerpiece of his agenda, Proposition 76, offered political grist for the unions: It would have given more budget authority to the governor -- a power grab by labor's account -- and make complex changes in the minimum school-spending rules that California voters approved in 1988.
The therapeutic blockade of VEGF by bevacizumab in CRC patients induces complex changes in the stromal compartment of the tumour lesion, including the loss of chaotic microvessels, remodelling of the vascular wall and a reduction in the interstitial fluid pressure (Willett et al, 2004).
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