Sentence examples for by complementarity of from inspiring English sources

Kuo et al. analyzed a gene regulatory network model in which interactions are defined by complementarity of binary 'protein' and 'cis-regulatory' sequences.

The locus of retroposition is, apart from a preference for ubiquitous A/T-rich target sequences only determined by complementarity of the retroposed RNA 3'-end and a ragged-ended DNA strand for priming.

Altogether, these data indicate that recruitment of ExSpeU1 by complementarity on intronic sequences downstream of the exon corrects multiple splicing mutations located either at 5′ or 3′ splice sites or in exonic regulatory elements.

The binding of antibody to antigen is principally generated by complementarities of the binding surfaces, which allows various interactions between the two molecules including the formation of hydrogen bonds, salt bridges, and van der Waals interactions [ 43].

ExSpeU1s bind by complementarity to intronic sequences downstream of the exon and rescue different types of splicing defects associated to exon skipping.

In conclusion, a single ExSpeU1 appropriately loaded by complementarity to intronic sequences downstream of the exon rescues correct splicing impaired by different mutations and recover the corresponding protein biosynthesis and function in model gene systems.

In minigene expression systems, loading of U1 snRNA by complementarity to the normal or mutated donor splice sites (5′ss) corrected the exon skipping caused by mutations at the polypyrimidine tract of the acceptor splice site, at the consensus 5′ss or at exonic regulatory elements.

Furthermore, binding sites of nuclear hormone receptors are rather hydrophobic [32], which might be difficult for conventional docking since nonpolar interactions are often only approximated by steric complementarity of atoms [33].

The synergistic effect can be explained by the complementarity of the two processes: ultrasound more effectively destroys the initial bisphenol A compound, whereas the photo-Fenton system is better able to eliminate the bisphenol A by-products.

Specificity of the OCP to its target sequence is achieved by the complementarity of the two ends of the OCP to the target and the requirement of these ends to be adjacent for ligation.

In this case, both the synapsis and precise approach of the 3′ terminus (Poly-dA) into the active site is facilitated by the complementarity of the last three 3′-terminal bases of each molecule (AAA-3′/TTT-3′).