Sentence examples for by competitive binding of from inspiring English sources

Finally, VEGF signaling can be suppressed by competitive binding of semaphorins to NRP1.

In the first stage, formation of the GQ is mediated by competitive binding of cPDS and BG4.

This modulation is accomplished by competitive binding of DELLAs to JAZ proteins, which prevents interaction between JAZ and MYC2, thus promoting MYC2-induced responses such as LOX [ 61].

Using specifically tailored glycosylated dendrimers, our current assay employs the use of aggregation that is induced by competitive binding of multivalent components, which results in a fluorescence intensity that correlates to glucose concentration (Fig. 1 ).

These in vitro studies rely on drug displacement by competitive binding of 45 toward endogenous compounds whereas the corresponding in vivo application of cyclodextrin·drug complexes also benefits from the dilution of the container·drug complex from above to below Kd.

Caspase-8-generated cleavage fragments of XIAP inhibit further processing of caspase-3 intermediates by competitive binding of BIR1 and BIR2 (BIR1-2) to a neo-epitope in the caspase-3 p19 fragment.

It should be mentioned that the presence of serum glycoproteins (or specific antibodies) is likely, by competitive binding, to influence the biological availability of these galectins in the circulation.

Altogether, the results reported in Fig. 7 strongly suggest that SLPI modulates, at physiological concentrations (20 150 µg/ml) [6], [7], the CD4-PLSCR1 interaction by competitive binding to the CD4-binding region of PLSCR1.

PDE4 inhibitors block the cAMP-degrading action of PDE4 by competitive binding to the cAMP catalytic site, which results in a reduction in T helper (Th) 1, Th2, and Th17 immune responses [ 4].

Similarly, inhibin A, the heterodimer of INHA and INHBA gene products, antagonises the anti-proliferative action of activin A by competitive binding to cell surface activin type II receptors (ActRIIA/B) and inhibits downstream signalling in liver cells (Xu et al, 1995; Lewis et al, 2000; Massague, 2000).

The immunoreactivity of 111In-bevacizumab was assessed by competitive binding to VEGF expressed on 2F11 cells.