Sentence examples for by comparing wild type from inspiring English sources

By comparing wild type with mutant huntingtin overexpressing striatal neurons, we addressed the question of the consequences of altered proteasome function.

By comparing wild type (WT) and Cx30 null mice, our results provide direct experimental evidence demonstrating that targeted deletion of Cx30 significantly compromised intercellular transfer of metabolically-important molecules among the supporting cells in the cochlea.

By comparing wild type and PT-deficient B. pertussis strains in the mouse model, our group has recently shown that PT contributes significantly to bacterial growth in the respiratory tract by effects on host cells of the airways, including inhibitory effects on the protective role of resident airway macrophages [4], [5], [6].

In order to select significant gene markers from the candidates selected by DEGs, we need to investigate which candidates are involved in the regulatory roles that caused phenotypic differences by comparing wild type (WT) and knockout (KO) mice.

To confirm or refute this hypothesis, we studied the importance of the NF-κB pathway by comparing "wild type" cells to cells manipulated in silico to show no TNF induced NF-κB activation.

The power law dependence of the limiting adaptation speed on both mutation rate and population density could be tested by comparing wild type with a mutator strain (Shaver et al. 2002) and by manipulating the thickness of the colony, respectively.

Endogenous NO production was examined in roots by comparing wild-type and mutant seedlings loaded with the permeable NO-sensitive dye fluorophore DAF-2 DA.

Here we directly test this hypothesis by comparing wild-type poliovirus to synthetic viruses carrying re-engineered capsid sequences with hundreds of synonymous mutations.

By comparing wild-type and Δ scpA mutant supernatants, we observed Staphopain A-dependent cleavage of the CXCR2 fusion protein.

The key factors for determining TNF sensitivity were explored by comparing wild-type and E1A/Ras-transformed MEFs.

We therefore hypothesized that cell death was the mechanism underlying sexual differentiation of the CALB-SDN, and tested this by comparing wild-type and Bax knockout mice.