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The observed susceptibity of cyclin D1-HA/FHL2−/− cell lines to Ras-induced transformation led us to examine the p53 status of these cells by comparing p53 expression levels in basal conditions and after doxo treatment.
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This migration failure can be observed by comparing Lhx6 expression in the heterozygote and mutant forebrain (Figure 1 E and E' respectively).
Since we have previously shown that TLR2 is essential for the induction of the foamy phenotype in ML-infected macrophages (Mattos et al., 2010), we next assessed whether ML-induced upregulation of CD36 relies on TLR2 signalling by comparing CD36 expression in in vitro infected macrophages derived from WT versus TLR2−/− mice.
We identified cancers that expressed elevated PIK3R3 by comparing PIK3R3 mRNA expression in the tumor samples with their expression in control tissues from the same patients.
Here, we addressed this concern by alternative, more quantitative approach, i.e. by comparing Panx1 gene expression levels in endothelium-intact and endothelium-denuded arterial preparations.
We investigated this hypothesis by comparing FGFR1 and FGFR3 expression at both mRNA and protein levels in normal and osteoarthritic chondrocytes.
To examine whether CDKN1A/p21 is regulated cooperatively by MBD4 and DNMT1, we compared CDKN1A/p21 expression in cells transiently depleted of MBD4, DNMT1, or both (Fig. 2A).
T-tests were used to compare CCR9 expression by RA and normal monocytes using flow cytometry (significance level <0.05).
We also compared LMNB1 expression obtained by quantitative PCR between patients with MI and patients with atypical chest pain and without MI.
This result is in agreement with our previous data [ 19] obtained by comparing ERC4 messenger RNA expression between independent normal reduction mammoplasty samples and a group of ER-positive/PR-positive breast tumors.
By comparing 383 GRG (Additional file 4) expression in MSC differentiated in one or the other differentiation pathway we retained 67 genes specifically associated with the myogenesis out of 383 studied.
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