Sentence examples for by comparing methylation patterns from inspiring English sources

Here we further explore ancestral relationships between human colon crypts by comparing methylation patterns from crypts separated by different distances (at least 15 cm apart, within the same 1 2 cm2 patch, directly adjacent, and branched crypts).

In humans, the role of global DNA methylation in colorectal tumourigenesis has primarily been investigated by comparing methylation patterns in colorectal tumour tissue, with matched adjacent normal appearing tissue obtained from the same patient [ 37- 42] or with normal colon tissue from non-diseased control subjects [ 37, 38].

Recently two other studies comparing methylation patterns among many species using BS-Seq technology briefly reported genome methylation patterns for japonica rice strain Nipponbare[ 18, 19].

Researchers will look at MHC regions in about 20 tissues, mainly various classes of immune cells, and they will compare methylation patterns of inactive cells with ones riled up by pathogens or autoimmune diseases.

Therefore, the starting point of our analysis compares methylation patterns between cells with relatively known ancestries.

Wilson et al (2006) compared methylation patterns with copy number profiles in lung cancer cells.

By comparing the methylation patterns between transcription factors, alternated methylation level around the TFBS suggests the binding of the transcription factor may be associated with DNA methylation.

We also demonstrated that complex DNA methylation domains that regulate imprinted genes can be mapped by comparing the methylation patterns in different tissues and different gestational ages of placentas.

In comparing the methylation patterns of tumors and nonmalignant lung tissues from the same patients, there were many discordancies where the genes methylated in nonmalignant tissues were not methylated in the corresponding tumors.

Potential regulatory DNA methylation sites were identified by comparing DNA methylation and gene expression patterns in hundreds of tumors from TCGA datasets and selecting sites with an inverse methylation and gene expression correlation (TCGA, https://tcga-data.nci.nih.gov/tcga/) [ 33, 34].

By comparing banding patterns after digestion with methylation-insensitive and methylation-sensitive restriction endonucleases, we found that TDCPP altered the status of zygotic gDNA methylation at 2 hpf but not at 10 or 24 hpf.