Sentence examples for by comparing methylation levels from inspiring English sources

DMRs for each sample were defined by comparing methylation levels to wild type in 100 bp bins across the genome.

This was verified by comparing methylation levels of individual alleles to total methylation levels in a panel of 10 peripheral blood DNA samples from healthy individuals that were informative for a G/A polymorphism (Fig.  1C).

We determined the level of global leukocyte DNA methylation using relative quantification of 5mdC by HPLC, and we compared methylation levels between cases and controls with nonparametric statistical tests.

To test this further we compared methylation levels of those CpGs mapping to genes upregulated in granulocytes and lmphocytes between healthy controls and post-treatment cases with and without active disease (as determined by CA125 levels) (Figure S4).

Step iii: Hyper and hypomethylated genes are defined relative to normal by comparing the methylation levels of each methylation state to the mean of the DNA methylation levels of normal tissue samples using a Wilcoxon rank sum test.

We investigated the possible bias due to the presence of non-epithelial cells by comparing the methylation levels of these layers in a subset of 10 gastric cancer patients.

Specifically, we used the SMP frequency spectrum in the entire gene body within one population in the test, but Heyn et al. identified any single cytosine site bearing differential population methylation pattern by compared the methylation level among three populations and used chimpanzee as the outgroup for the local selection analysis.

Differential methylation was assessed by comparing the mean methylation level (b-value) of samples with the mean b-value of the corresponding adjacent tissue by using BeadStudio (San Diego, CA, USA) and Qlucore Omics Explorer 2.0 (Qlucore AB, Lund, Sweden) software.

This was initially tested by comparing overall DNA methylation levels in T cells from patients with active lupus, inactive lupus, or other rheumatic and inflammatory diseases and healthy controls.

By comparing average DNA methylation levels between all FTLD patients, AD patients, PD patients and controls across the different amplicons, we observed a slight, but highly significant increase in DNA methylation from 57% to 62% in FTLD patients in amplicon A-1.

We grouped N. vespilloides genes as methylated or unmethylated by comparing the level of methylation of an individual gene with the average level of gene methylation found across all genes.