Sentence examples for by comparing mRNA levels from inspiring English sources

Much of this quantitative work was done by comparing mRNA levels.

We next evaluated the impact of DNA-level alterations on mRNA expression of CUL3, KEAP1, and RBX1, by comparing mRNA levels in samples with and without inactivating DNA-level alterations affecting any of the complex component genes for samples with available expression data for these genes (n = 37).

Therefore, we identified normally expressed genes in normal mouse thyroid tissue by comparing mRNA expression levels for transcripts with previously known and unknown expression patterns in mouse thyroid [29].

The changes in the expression were evaluated by comparing the mRNA levels in conidia incubated in G+ and in conidia incubated in G−.

We evaluated this possibility by comparing the mRNA levels of FVE, FLD, FCA, FPA, LD, FY, and FLK genes between wild-type and brm mutant plants.

By comparing the mRNA levels of the healthy (control and L. johnsonii fed) with diabetic animals two primary responses were observed: (i) genes negatively correlated with healthy status (Cat and GR), and (ii) genes negatively correlated with L. johnsonii administration (Sod2 and Gpx1).

These analyses were done by comparing APOBEC3B mRNA levels and tumor mutation counts.

This method was previously validated by comparing HER2 mRNA levels in 55 formalin-fixed, paraffin-embedded samples, in which HER2 status was evaluated by IHC and fluorescence in situ hybridisation (Barberis et al, 2008).

Next, we tested whether the hypothalamic orexigenic and anorexigenic genes responded properly to variations in the peripheral energy balance in BBS mice by comparing the mRNA levels of these neuropeptides in normally fed and 48 h fasted animals.

To validate the microarray data, a real-time PCR assay was performed to monitor gene expression in both wild type and mutant strains by comparing the mRNA levels of selected genes to a stable housekeeping gene (e.g., actin) using delta-delta Ct (threshold crossing value) calculations.

For example, the authors focus on cyclin A2 and by comparing its mRNA level to protein level they conclude that transcription is a major factor in regulating cyclin A levels.