By comparing gene expression in animals expressing a dominant, activated beta-catenin protein to that in control animals, we identified 166 differentially expressed genes, of which 104 were up-regulated and 62 were down-regulated.
A comparative study was conducted by comparing gene expression profiles between each of the four selected tissues (cecal tonsil, ileum, liver, and spleen).
Gene categories showing significant transcriptional changes were identified by comparing gene expression under regular conditions with expression under the other nine conditions.
After calculating gene expression levels, the differentially expressed genes (DEGs) were screened by comparing gene expression levels.
We have recently identified genes expressed in GIST, but not in normal KIT-ir ICC, by comparing gene expression profiles of the antrum of transgenic mice harboring the oncogenic Kit K641E mutation [13] and WT littermates, using cDNA microarray.
We determined actual transcriptional OTEs by comparing gene expression profiles in siRNA-treated cells vs untreated controls, and identifying differentially expressed transcripts.
Biologists can now hope to understand many diseases at the level of the human cell by comparing gene expression in normal and diseased tissue.
CNOT-dependent genes were identified by comparing gene expression between pIND CNOT + Dox (lacking the respective CNOT subunits) versus pIND Luci + Dox (containing the respective CNOT subunits) to eliminate gene regulatory events attributable to Dox treatment.
"We identified a COPD-specific signature by comparing gene expression changes in COPD-derived chips exposed or not exposed to smoke and subtracting the changes that we see in chips made from healthy lung chips.
This study aimed to determine the developmental genes and molecular pathways that are involved in diabetic embryopathy, by comparing gene expression profiles in the yolk sacs between the embryos of diabetic and control rats by using DNA microarray analysis.
The transcriptome response to radiation exposure was derived by comparing gene expression in samples before and after irradiation.
