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This became apparent by comparing different cell types from patients with I-cell disease, also known as Mucolipidosis type II.
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The authors conclude that local chromosomal environment affects initiation rates by comparing different clonal cell lines that accrue different amounts of total labeled construct mRNA.
Remarkably, Wildermuth [ 3] noticed, by comparing different biotrophic interactions of plants, that host cell polyploidy is a common feature of symbiotic interactions with rhizobium bacteria and arbuscular mycorrhizal fungi, as well as parasitic interactions with fungi and nematodes.
Therefore, the developmental process of somatic embryogenesis was analysed in the ornamental crop Cyclamen persicum by expression profiling, comparing different developmental stages of embryogenic cell cultures, zygotic vs. somatic embryos and embryogenic vs. non-embryogenic cell cultures.
By comparing cells from different generations of telomerase-null mice with human cells, we show that cells from late generation telomerase-null mice, which have substantially short telomeres, contain mostly telomeric γ-foci.
In addition, by comparing cells from different generations of telomerase-null mice, we show that telomere length, rather than other differences between human and mouse, determines the differential pattern of senescence-associated DNA damage.
We next performed the pathway analysis by comparing two different TKI-resistant cell lines (nilotinib versus imatinib).
The results of tumorous images formed by 4T1-PB-2R/PBase cells were quantified and compared among different cell amount after 1 day and 7 days of subcutaneous (s.c).
The time resolution of the image data was sufficient to unambiguously track cells over time by comparing cell shape and position at different time points.
To compare different expression levels directly, unstressed cells were marked by staining their nucleic acids with DAPI.
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