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To estimate the influence of out-of-home care on reading scores, attendance, and suspensions by comparing a matched sample of maltreated children who entered out-of-home care and maltreated children who remained at home.
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Somatic SNVs are identified by comparing a tumor sample with a matched normal sample (usually blood from the same patient).
We performed SegSeq [ 54], a widely used method to identify copy number variation (CNVs) by comparing a tumor sample with a matched normal sample, to infer somatic CNVs in ESCC genomes based on WGS reads.
While most complex disorders generally can confirm the strength of their findings by comparing against a matched background cohort, the nature of studying rare monogenic disorders mean that there is often insufficient sample size to conduct a rigorous statistical analysis on the strength of the finding.
Nevertheless, we tried to overcome these limitations by comparing a relative uniform high-volume, matched by tight criteria for classifying radiological change such as progressive radiolucency in zone 4 [ 28].
The first step consisted of the application of a computer-scoring algorithm to identify clearly true and clearly false matches by comparing a SEER patient's record with an NLMS record.
In turn, the diurnal variation was assessed by comparing, using a matched t-test, the morning session vs. the afternoon session on day 5.
Found by comparing the matched (by BLAST) position to the annotations in genbank entry AF486866.
Filter 2 Somatic variants were called by comparing matched normal and tumor tissues.
Therefore, we analyzed the expression of the different TRAIL splice variants by comparing matched neoplastic and non-neoplastic tissue samples.
In summary, we performed a genome-wide study of LOH and CNA in ESCC patients using the Affymetrix 10 K SNP chip by comparing matched germ-line and tumor DNA.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com