In an effort to elucidate the molecular mechanism of action of chemopreventive rexinoid bexarotene and to identify potential biomarkers of significance, here we report a comparative transcriptome profiling of three mouse mammary cancer models by Serial Analysis of Gene Expression (SAGE).
The main purpose of this study was to glean virulence and immunomodulatory F. hepatica genes through comparative transcriptome profiling with the transcriptomes of non-parasitic related organisms by focusing on the genes which are evolved in lineage-specific manner, under positive selection and show similar motifs of host immune system genes involved in cytokine signaling.
To further elucidate the molecular basis of estrogen-dependent breast carcinogenesis, we here report a comparative transcriptome profiling of invasive breast tumors based on ERα status obtained by SAGE.
A comparative transcriptome profiling between a riboflavin-producing Bacillus subtilis strain RH33 and the wild-type strain B. subtilis 168 was performed, complemented with metabolite pool and nucleotide sequence analysis, to rationally identify new targets for improving riboflavin production.
In the present study, we performed comparative transcriptome profiling of A. mongolicus in response to drought and cold and identified thousands of the DEGs regulated by each stress.
Comparative transcriptome profiling of the rpoE deletion mutant and the wild-type parent established that expression of 68 genes was significantly influenced (> 3-fold change) by the loss of the sigma factor (Fig 3A, Supplementary Table S2).
Comparative transcriptome profiling suggested that PUSABGD72 possesses a different gene expression pattern from ICCV2 under drought stress.
Zhao et al. [ 21, 22] conducted comparative transcriptome profiling at both csgl1 (mict) and trichome-less (tril) mutants.
The recent comparative transcriptome profiling of invasive breast carcinoma based on ERα status has identified NLP (KIAA0980) as a novel oestrogen responsive genes (Abba et al, 2005).
We performed comparative transcriptome profiling of DMSO-, Band, and TCDD-treated Hepa-1c1c7 and c35 cells using the Affymetrix GeneChip Mouse Genome 430 2.0 Array (Santa Clara, CA).
