Sentence examples for by comparative sequencing of from inspiring English sources
Finally, we found evidence for polyclonal and sequential metastatic spread of murine SCLC by comparative sequencing of families of related primary tumors and metastases.
The first demonstrations of microcolinearity (also called microsynteny) by comparative sequencing of orthologous chromosomal regions [17, 84] indicated that overall genomic similarity could be converted into very local analyses of the evolved structure and function of genes that were all derived from a known ancestral locus at attributable dates.
Ancestral sequence of the targeted genomic region (WNK1 exon10–intron10–exon11) was assessed by the comparative sequencing of the genomic DNA from WNK1 AluYb8 insertion noncarrier and carrier (Alu/Alu) human homozygotes as well as from a chimpanzee (Pino).
Therefore, it has been attempted to identify the specific genetic determinants of plasma TG levels, and a novel member of the apolipoprotein family, apolipoprotein A5 (APOA5), was identified by the comparative sequencing of the APOA1/C3/A4 gene cluster region [ 3].
We also investigated the molecular epidemiology of the outbreak by comparative sequence analysis of the isolates obtained in this study with reference strains of JEV.
The primer combination was tested for specificity on selected pure cultures, and by comparative sequence analyses of randomly selected clones of a clone library generated with these primers from soil DNA extracts.
By comparative sequence analysis of ompA, csuE and blaOXA-51-like genes, a set of eight primers was designed for an alternative multiplex-PCR to distinguish the five CC 113/79, 103/15, 109/1, 110/25 and 118/2.
Our results successfully revealed candidate nsSNPs and associated genes for drought tolerance by comparative sequence analysis of 16 maize inbred lines.
All putative H. annosum SNPs/InDels detected by comparative sequence analysis of the six genomes were confirmed in the genotypes for which individual loci were sequenced (see supplementary alignment S1, Supplementary Material online).
Reichwald et al. [ 56] similarly found by comparative sequence analysis the existence of this additional stretch of sequence 3′ to the previously reported poly(A) site, which terminated in an alternative poly(A) site.
This is supported by the occurrence of recombination (see former paragraph) and by comparative sequence data at three of the DIP-linked marker regions analyzed, S4, S7 and S11.
