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Assigning protein functions by comparative genome analysis: protein phylogenetic profiles.
These highly variable genome regions have been analyzed for a few bacterial taxa by comparative genome analysis [ 1].
Detailed information on all clusters predicted by comparative genome analysis including the positions of all sequences can be found at: [ 25] and [ 41].
1. Pellegrini M, Marcotte EM, Thompson MJ, Eisenberg D, Yeates TO: Assigning protein functions by comparative genome analysis: protein phylogenetic profiles.
The aims of this study were as follows: (1) to add knowledge concerning QTL mapping of the fatty acid composition in B. napus; (2) to predict candidate genes of major QTLs for different fatty acids' biosynthesis by comparative genome analysis; and (3) to construct a regulatory pathway for fatty acids metabolism in B. napus.
By comparative genome analysis of five Caenorhabditis and eight Drosophila species, we found that the likelihood of intron loss is highly influenced by the degree of sequence homology at exon intron junctions: a significant elevated degree of microhomology was observed for sequences immediately flanking those introns that were eliminated from the genome of one or more subspecies.
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Extensive recombination among STB genomes, as identified by our comparative genome analysis, might be partly responsible for the discrepancy in dN/dS ratios between the MTBC and STB groups, as it could more efficiently oppose fixation of slightly deleterious mutations than in the more clonal MTBC population39.
Another enduring question that was illuminated by a comparative genome analysis strategy was the nature of the DNA in the eukaryotic nucleus.
The amplicons sequenced were selected based upon their likelihood to be evenly distributed throughout the tall fescue genome, as determined by a comparative genome analysis involving wheat (Triticum aestivum L ., perennial ryegrass (Lolium perenne L). and Brachypodium distachyon.
The first step, integration, is quite common in plants, as has been shown by both comparative genome analysis and direct experimental methods (Huang et al. 2003; Shahmuradov et al. 2003).
Since the bovine genome is not yet completely annotated we minimized any gene structure bias in the input data by carrying out comparative genome analysis on the orthologous subset of AS genes for the three species.
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