Sentence examples for by comparative gene analysis from inspiring English sources

SPRN was identified by comparative gene analysis [ 37]; it encodes Shadoo (Sho, shadow of prion protein), a highly conserved protein that has possible functional links with the prion protein [ 38], and different genetic variants have been associated with risk for either variant or sporadic CJD [ 35].

By exploiting comparative gene analysis we further succeeded in identifying αvβ8 integrin as a target receptor thus solving a major challenge of directed evolution approaches and describing a promising candidate receptor for cutaneous gene therapy.

This was followed by comparative gene expression analysis.

Radioresistance-associated pathways were determined by comparative gene expression analysis of radioresistant cell line (Panc-1RR) with that of parental cell line exhibiting relative radiosensitivity (Panc-1).

These results were further confirmed by comparative gene expression analysis of clinical MB samples, which showed a highly significant positive association between JAG1 and HES1 mRNA transcript levels.

Our sequencing strategy helped remove, at least to a chromosomal level, the difficulties associated with candidate gene identification by comparative gene expression analysis in apomictic and sexual systems which lack, due to the apomictic process, an ability to generate isogenic lines that vary only in their mode of reproduction.

This development set the stage for the widespread use of genome scans followed by linkage analysis or homozygosity/autozygosity mapping, followed by comparative positional candidate gene analysis.

In the present study, we performed a comparative gene expression analysis of normal human brain tissue and tissue affected by Alzheimer's disease, using the RNA-Seq technique.

CHS8 gene (LOC_Os05g12240) was selected for comparative gene expression analysis between the two cultivars.

By comparative analysis of gene expression among 6 different serotypes of A. pleuropneumoniae we identified a common set of presumably essential core genes, involved in iron regulation.

By comparative analysis of gene expression, histology and viral load, the temporal and spatial regulation of immune responses were characterised and novel immune genes identified, ultimately leading to a more complete understanding of host-virus responses and pathology and protection in Atlantic salmon during CMS.