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However, by collapsing genotype data to a contingency table of alleles, we are implicitly assuming Hardy-Weinberg equilibrium at each SNP, and may inflate type I error rates if violated.
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We begin by constructing contingency tables of alleles at the two SNPs in each phenotype group by collapsing the sample genotype data (Table I).
This was discussed and was reconciled by collapsing two data categories into one.
In the case of spectral cues, this was done by collapsing the data across azimuth for the other ear.
Power may also be gained by collapsing multi-locus genotype information into a single degree of freedom test [ 3].
The combined effects of LIG3 rs4796030 and PARP1 rs8679 was assessed by collapsing unfavourable genotypes (AC + AA and CT + CC genotypes, respectively) for analysis on bladder cancer risk (Table III).
We partitioned the data into gene-centric bins and collapsed genotypes of low frequency variants (defined here as MAF ≤0.05) into a single count coupled with univariate analysis.
We conducted a pooled analysis of previously-identified SNPs by combining genotype data from 3,973 invasive EOC cases and 3,276 controls from the Ovarian Cancer Association Consortium.
Therefore, clearly classifying the F2 plants into subgroups according to mesocotyl length by the genotype data was impractical.
Their relationships were determined from interviews and confirmed by genotype data (see Methods, Genotyping).
These include new ways to estimate allele frequency and a kinship matrix from genotype data, statistics for collapsing family-based data, and a correction factor for relatedness affected and unaffected pairs within pedigrees.
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