A prognostic index was then derived by classifying the results obtained for each of the four markers into three categories.
For each biomarker assessed by IHC, a modified H-score [ 23] was derived by classifying the intensity of staining according to three categories (1+, 2+, 3+) and assessing the percentage of tumor cells within each staining intensity (P1, P2, P3, respectively).
By classifying the literature into three major areas, namely, supply information management, demand information management, and values of information and supporting technologies, we derive insights into the current state of knowledge in each area and identify some associated challenges.
All cases were cross-validated by the "leave-one-out" method, where each case in the analysis is classified by the functions derived from all cases other than that case.
In the discriminant analysis, we used leave one out classification where each case in the analysis is classified by the functions derived from all cases other than that case.
In addition, a cross-validation was performed to assess the generalizability of the predictive models; each case was classified by the functions derived from all other cases (leave-one-out-classification).
Projection averages were derived by classifying particles of similar orientation and structural conformation using reference-free multivariate statistical analysis (van Heel et al., 1996), and iterative stable alignment and clustering procedures (Yang et al., 2012).
In cross-validation, each case is classified by the functions derived from all cases other than that case; 83.9% of original and 83.8% of cross-validated grouped cases were correctly classified.
aIn cross validation, each case is classified by the functions derived from all cases other than that case.
In cross validation, each case is classified by the functions derived from all cases other than that case.
