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The highest correlation (r2 > 0.8) was shown by classical markers of cellular stress, such as the aryl hydrocarbon receptor, MAP kinase 13 and hypoxia inducible factor.
To examine whether the relation between DTI parameters and cognition was mediated by classical markers of small vessel disease, we adjusted significant group × DTI parameter interactions on cognition for the presence of cerebral infarcts and total WMH load.
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To determine the extent of cardiovascular injury caused by PM, in general, classical markers of inflammation up-regulated in most disease conditions are analyzed.
Consistently, high-salt-induced suppression of protein levels of MMR and IRF4, two classical markers of M IL4), was alleviated by STAT6 overexpression in RAW264.7 cells.
We, therefore, tested whether the predictive value of suPAR was equal or superior to classical markers of inflammation and bacterial infection by using ROC curve analyses comparing suPAR with CRP, procalcitonin (PCT) and white blood cell count.
In concordance with the currently acceptable dogma regarding apoptosis17, uttroside B induced all classical markers of caspase-dependent apoptosis, as evidenced by presence of apoptotic bodies and cleavage of caspases and PARP.
The latter acquire the classical markers of this pathway.
Myoblast cells were then co-stained for classical markers of podosomes: actin and cortactin (Figure 2A).
PIK3CA mutations are associated with classical markers of good prognosis and signatures of PI3K pathway activity.
We observed classical markers of cellular senescence in both RS and dox-induced SIPS.
Fever and leucocytosis, the classical markers of infection, have only moderate sensitivity and specificity.
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