Sentence examples for by changing gene expression from inspiring English sources
Based on this, we postulated that S. aureus might induce cytoprotective mechanisms by changing gene expression profiles inside macrophages similar to obligate intracellular pathogens, such as Mycobacterium tuberculosis.
Similarly, single-celled organisms, such as bacteria, can adapt to survive and grow in different environments by changing gene expression levels.
Thus, we hypothesized that the vitamin C-induced global increase of 5hmC could, at least in part, be responsible for the phenotypic consequences of A2058 cells by changing gene expression profiles.
These results suggest transcription factor AtOFP8 could change epicuticular waxes content and composition, perhaps by changing genes expression.
However, many insertions that do not cause disease may still influence the expression of the genes in which they insert, thus predisposing cells or individuals to disease by slightly changing gene expression.
A solid body of evidence shows that offspring of obese mothers, be it rodents, monkeys, or humans (5 – 7), are programmed to become overweight themselves, in part by epigenetic mechanisms changing gene expression into adulthood.
That is, the oxidized guanine base may itself behave as an epigenetic marker that alters DNA structure, changing gene expression levels by enhancing the formation of a specific secondary structure that recruits a BER enzyme as a transcription factor.
Previous studies reported that CNVs can modify gene expression level and lead to consequent phenotypes by changing gene dosage (Zhang et al., 2009; Dong and Wang, 2015).
If FTO is involved in the phenotype, the observed methylation change could affect expression by changing gene-body methylation or influencing the isoform balance by modifying exon inclusion or exclusion [59].
Animal evolution works not so much by changing genes, Carroll maintains, but by changing when and where a conserved set of genes is expressed.
