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The results indicate that the motor deficits during the absence of D1R-mediated dopaminergic transmission cannot be explained simply by changes in spontaneous firing rates in the EPN.
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Furthermore, the altered profile of ultrasound emission was accompanied by significant changes in spontaneous motor behavior on PND 12: CPF-exposed pups displayed less Pivoting – a typical neonatal motor pattern in rodents – associated with a higher level of immobility.
Plasticity of excitatory connections would be further enhanced by the opposite changes in spontaneous firing of broad- and narrow-spiking neurons.
In this study, we set out to extend previous work on the effects of osmolarity on evoked neuronal events by determining if there are acute changes in spontaneous neuronal excitability upon switch to hypoosmolar ACSF (hACSF).
To detect changes in spontaneous activity induced by light, the raster and peri-stimulus time histograms were generated from 10 stimulus blocks using 50 ms bin widths.
We identified mental fatigue-related changes in spontaneous EEG variables.
Thus, the impairment in LTP in TG rats is unlikely to be caused by any change in spontaneous or evoked synaptic transmission mediated through AMPA receptors.
Potential explanations for this association include surgical management of miscarriage, which can lead to cervical damage (see below). 4 The association could, however, also be explained by other factors such as maternal stress, 12 or by changes in the nature of the previous spontaneous losses.
The spontaneous initiation of walking is accompanied by changes in the firing pattern of several SEG and SupEG descending interneurons.
Uterine quiescence during pregnancy and the increased activity associated with the spontaneous onset of labour are likely to be reflected by changes in myometrial receptor function [ 6, 7].
Because individuals with an ASD-like presentation can maintain rigid habits and frequently show a strong insistence on sameness and are upset by change in routine, the Y-maze spontaneous alternation test was used to evaluate perseveration by monitoring the resistance to the change of arm choice (Fig. 5B).
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