Sentence examples for by changes in disease from inspiring English sources
Our results could also have been influenced by changes in disease diagnosis and management over time.
Comparison of the incidence of haematological malignancies across countries and over time has been complicated by changes in disease classification systems.
All patients were monitored for toxicity and clinical efficacy, the latter being assessed by changes in disease burden and quality of life measurements.
This increase in cerebral lymphoma is not adequately explained by improvements in the precision of diagnosis or by changes in disease coding or cancer registration practice.
As a means of confirming findings using the SEM-criterion approach, we also used an anchoring technique, whereby we examined changes in the DLQI total score by changes in disease severity using the patient-assessed mean pruritus score.
The observed treatment patterns are consistent with results of previous studies showing reduced response with subsequent anti-TNF use compared with the first anti-TNF therapy as measured by changes in disease activity or treatment continuation [ 21- 24].
There was no statistical difference in changes to the satisfaction care by change in disease activity (− 0.01 vs. -0.02 vs. – 0.04, p = 0.43).
TCZ efficacy, assessed by change in disease activity score at 28 joints (DAS28) at weeks 12 and 24 or by ACR 20/50/70 proportional changes at week 24, was similar to that previously observed and differed significantly from that of placebo (see online supplementary figure S1).
The correlation between clinical response to rituximab, as measured by change in disease activity score using 28 joint counts (DAS28), and percentage change of SSI pre- to post-treatment was examined; however, none of the autoantibodies or total immunoglobulin examined covaried with DAS28 in a statistically significant manner.
Moreover, epidemiological changes exceed quantitative changes in the disease burden and are also characterized by changes in the disease course.
The therapy response was determined by changes in the disease activity score (DAS28) 3 months after the start of treatment.
