Sentence examples for by changes in calcium from inspiring English sources
In several experimental systems (Jurkat T cells, murine T-cell hybridomas), TNF-alpha appears to cause a downregulation of signaling through the TCR, revealed by changes in calcium flux, activation of p21, p23 and ZAP70, and a decrease in nuclear activation of NF-kappaB.
Drp1-dependent mitochondrial fragmentation is influenced by changes in calcium levels [56] and by phosphorylation at Ser637 [40].
Although synaptic potentiation and depression are both triggered by changes in calcium concentration, they likely require very different concentration profiles [4] [6].
Disturbance in the ER leads to ER stress which can be caused by accumulation of unfolded proteins and by changes in calcium homeostasis within the ER [21].
Aging cardiomyocytes display prolonged contraction and relaxation caused by changes in calcium homeostasis [ 18].
Desensitization of D2S was readily reduced by changes in calcium signaling (intracellular stores and L-type calcium channels), but not in vivo cocaine.
The mechanisms involved in the modulation of force generation by ROS are not fully established, but published data indicate that the variation of force in response to shifts in the redox balance may be mediated by changes in myofibrillar calcium sensitivity (2) and/or a reduction in calcium release from the sarcoplasmic reticulum (1, 57).
Although we do not have direct evidence to suggest that Psn-induced wing notching is attributed to disruptions of intracellular calcium at the wing margin, it is known that Notch proteolysis and activity is impacted by changes in internal calcium stores.
The fact that the activation of plant defence responses is dependent on changes in both cytosolic calcium and cGMP [ 26] further substantiates the importance of the PSKR1 switch mediated by changes in intracellular calcium.
Both pathways are dynamically regulated by changes in intracellular calcium concentration [Ca2+]i, which occur in the form of push-pull interactions between Ca2+ entry and clearance [reviewed in 1], [2].
Consequently, any effect of EGTA-AM on synaptic transmission must be caused by changes in presynaptic calcium.
