Sentence examples for by certain cell types from inspiring English sources

Focusing on simian virus 40 (SV40) and mechanisms of malignant transformation in cells, Jaenisch moved toward using mice as models for cancer research and became interested in the increased susceptibility to cancer exhibited by certain cell types.

Metastasis is a nonrandom and organ-specific process undertaken by certain cell types.

In line with its multiple roles it can be located in the nucleus as well as in the cytoplasm and can even be released passively by necrotic cells or actively secreted in response to inflammatory signals by certain cell types [ 83, 84].

The PI3K/Akt pathway is activated by hypoxia in certain cell types and interference with the Akt reduces accumulation of HIF in response to hypoxia [ 27].

Emerging evidence supports a complex crossregulation between interferons and TNF, including induction of interferons by TNF in certain cell types [ 33] and extensive crosstalk at the level of signal transduction.

p38MAPK inhibitors failed to reduce fenretinide-induced DR expression to basal levels, suggesting that other factors may also upregulate DR. c-Jun N-terminal kinase is an additional ASK1 substrate that is activated by fenretinide in certain cell types (Kang et al, 2008; Appierto et al, 2009).

Enrichment of certain cell types by sorting or laser capture microdissection prior to analysis might be desirable.

This gives the possibility to construct a more comprehensive map of gene regulatory networks for certain cell types by integrating transcriptional and post-transcriptional regulations of gene expression.

Whilst many genes are probably induced by IFN-γ only in certain cell types or under certain conditions, these ubiquitously-responsive genes are likely to play key roles in the response to IFN-γ of numerous cell types (just as IFNaR1 and IRF1 do).

The close proximity with which STAT1 regulates the expression of "core" IFN-γ-inducible genes suggests that many of the STAT1 binding sites identified by ChIP-chip may be involved in the regulation of genes, alternative gene transcripts, or non-coding RNAs that are induced by IFN-γ only in certain cell types or only under certain conditions.

In other words, if two different TFs (e.g. the red circle and black circle TFs in Figure  1) cooperatively regulate the same regulons in certain cell types by binding to their respective CREs in CRMs, then their extended ChIP binding peaks from these cell types should overlap with one another to some extent.