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Randomisation was by central allocation of a unique number in order of qualification for treatment.
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To avoid biased allocation, randomisation is undertaken by central allocation using a computerized random number generator at the Internet Data and Information Center for Medical Research (INDICE), provided by the University Hospital Medical Information Network UMINN) in Japan.
Central allocation of health visitor tasks such as developmental checks or new birth visits resulted in a lack of consistency in work with the family, the report said.
Only 1% (10/1077) of RCTs reported reasonable allocation concealment, including central allocation and sealed opaque envelopes; 99% (1067/1077) of trials did not indicate the allocation concealment method.
Randomization to one of the two treatment arms (1 1 ratio) was done per center and stratified by age (<32 and≥32 years) by central remote allocation using randomly permutated blocks with an undisclosed fixed block size of four.
The date of entry into the study for the people in the screening group was the date of the screening appointment, evenly distributed throughout the two year screening period (January 1999 to December 2000) by central, random allocation.
Sealed envelopes and central allocation were used for allocation in the case of Fatovich et al. [ 15], but no detailed information on randomized sequence generation was reported.
Allocation concealment: Low risk of bias Participants and investigators enrolling participants could not foresee risk assignment because one of the following or an equivalent method was used to conceal allocation: Central allocation (including telephone, web based and pharmacy controlled).
Who picks up the bill will simply be determined by the allocation of property rights.
The central aspect of the concept is a stochastic MILP for the determination of an appointment scheduling setup configuration, which is defined by the allocation of walk-in and pre-scheduled appointment blocks in combination with the allocation of daily service times.
Concealment of allocation is assured by central randomization via consecutive randomization lists in the order of recruitment.
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