Sentence examples for by cell surface heparan from inspiring English sources

In many instances, virus cell interaction is mediated by cell surface heparan sulfate proteoglycans (HSPGs).

VEGF 121 and VEGF165 are secreted into the medium by producing cells, whereas VEGF189 and VEGF206 are sequestered by cell surface heparan sulfates [19], [22] [24].

16 Oligoarginines were reported to be internalised into mammalian cells through an endocytotic pathway, mediated by binding to cell surface heparan sulfates linked to proteoglycans, 17 followed by back-transport into the Golgi complex and endoplasmic reticulum.

It is concluded that the heparin-binding domain of fibronectin by itself can promote angiogenesis in endothelial cells possibly by interaction with cell surface heparan sulphate proteoglycans involving protein kinase C dependent signaling and making available more active form of vascular endothelial growth factor to the cells.

Binding Wnt ligands to frizzled receptors is regulated by the 6-O sulfation-desulfation of cell surface heparan sulfates (HSs) by sulfatase 1. Sulfated HSs bind to Wnt ligand with high affinity and inhibit Wnt signaling.

Fibroblasts and myofibroblasts in the skin use α5β1 or αv integrins to bind to fibronectin, whereas collagens are primarily recognized by integrins α1β1, α2β1 and α11β1 and to a lesser extent by other receptors such as cell surface heparan sulfate proteoglycans (syndecans) or discoidin domain receptors (Table 2).

Our results are consistent with those of Tan et al., who simultaneously described sulfate-mediated inhibition of EV71 entry by demonstrating the binding of EV71 to cell surface heparan sulfate glycosaminoglycan and the blocking of this binding by suramin.

Mice deficient in syndecan-1, a cell surface heparan sulfate proteoglycan expressed by mammary epithelial cells, exhibit normal primary mammary duct formation, but have a mild reduction in secondary and tertiary branching [29], [30].

Integrin expression and activity can be further modulated by other transmembrane proteins such as tetraspanins or cell surface heparan sulfate proteoglycans.

We show that V3C18 is a cell surface heparan sulfate proteoglycan, its topology being mediated by the FZC18 module.

Syndecan-1/CD138 (Sdc1) is a cell surface heparan sulphate proteoglycan that is highly expressed by epithelial and plasma cells.