Sentence examples for by cell surface class from inspiring English sources

Further strong evidence for the biological relevance of the results of TAP binding assays was provided in a study showing that TAP binding affinity paralleled closely the efficiency of epitope presentation by cell surface class I molecules [17].

The PI3K class I is activated by cell surface receptors and consists of two subfamilies, class IA and class IB, which are composed of heterodimers of catalytic and regulatory subunits, identified as p110/p85 and p110γ/p101 for class IA and class IB, respectively [ 6, 7].

Among this class of enzymes the most studied are class I that are activated by cell surface receptors.

One such class is the natural killer T cells (NKT), a special group of T cells characterized by cell surface expression of the NK receptor.

We have recently classified OAs according to cellular localization [ 4]: Class I (cancer cell surface antigens), Class II (soluble antigens and antigens expressed in the TME), and Class III (intracellular proteins expressed by cancer cells).

The mutation might give rise to peptides that may be presented on the tumour cell surface by class II molecules, and thereby induce immune responses against neoplastic cells.

Here, we demonstrated that MHC class I participates in EHV-1 entry into equine cells; however, pretreatment with anti-MHC class I antibody and the reduction of cell surface MHC class I expression by β2m knockdown did not alter the susceptibility of CHO-K1 cells to EHV-1.

Immature BMDC were produced from C57BL/6 mice [31] and the maturity level measured by lack of cell surface expressed MHC class II and other co-stimulatory molecules by flow cytometry [19].

Internalized antigen is carried to the cell surface by one class of MHC molecules, MHC class II, which promotes activation of CD4 cells.

By convention, peptides presented at the cell surface by MHC class II molecules (MHCII) are derived from internalized ("exogenous") antigen that is denatured and fragmented in the endocytic compartment and loaded onto MHC in the late endosome with the assistance of the H2-DM chaperone.

The quality of proteasome degradation will influence the nature of the peptides displayed at the cell surface by MHC class I molecules.