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It remains unaffected, however, by cell cycle position.
Similar to Lsk1p, and Lsc1p, Fcp1p displayed a constitutive nuclear localization that was not affected by cell cycle position, temperature, or the presence of LatA (Figure S1; data not shown).
FLIP expression levels are regulated by cell cycle position, by the transcription factor p53, and by the PI3K/Akt/FOXO31 pathway in other systems.
A monoclonal antibody that recognizes human ORC1 was used to localize ORC complexes in populations of human MOLT-4 cells separated by cell cycle position using centrifugal elutriation.
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Proliferating cells in Ω are additionally characterized by their cell cycle position c.
By defining the cell cycle position on a cell-by-cell basis, we next determined cell responsiveness to compounds.
Our flow cytometry results (Fig. 1) support this observation by indicating that cell cycle position is important for γH2AX focus formation after exposure to low but not high (> 20 μg/ml) MNNG doses.
Its localization was not affected by changes in temperature, cell cycle position, or by treatment with LatA (data not shown).
Genetic and proteomic changes may have substantial effect, by altering proliferation kinetics, cell cycle position, inhibiting apoptosis and regulate angiogenesis and cellular metabolism [ 2].
Cell cycle position was identified by the DNA content of cells as determined by propidium iodide (PI) staining.
The cell cycle distribution pattern is strongly disturbed by irradiation; in turn, radiosensitivity depends on cell cycle position and cell cycle progression [ 21].
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