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In contrast resistance to AI therapy may also develop by causing hypersensitivity to residual and exogenous estrogens.
9 It is tempting to speculate that biological agents may induce these reactions in a portion of susceptible patients by causing hypersensitivity to the given biological agents, 10 in part through the immunogenicity of the agents or by direct effects on cellular functions through the Fc portion of the products.
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A genetic background has been found for some RAU patients; those having positive family history for oral ulcerations have shown an increased frequency of human leukocyte antigen (HLA) types A2, A11, B12, and DR2. 2 Dietary patterns could be playing a role in the pathogenesis, either by causing hypersensitivity or by deficiency of some vitamins, proteins, or minerals.
Increased channel activity results in neural sensitization that causes hypersensitivity to sensory input and contributes to painful inflammation by a mechanism known as neurogenic inflammation.
Similar to loss of function of breast cancer susceptibility genes BRCA1 or BRCA2, ATM loss or mutation causes hypersensitivity to various clinical DNA-damaging agents50.
Overexpression of arn1+ confers canavanine resistance on cells, whereas its disruption causes hypersensitivity to canavanine.
The resulting increase in ER-α expression levels in these cells caused hypersensitivity to E2 [ 40].
These findings provoke a new question: how does the molecular action of BRM cause hypersensitivity to high-B stress?
Hangovers cause hypersensitivity to light and noise.
This species mainly causes hypersensitivity pneumonitis secondary to aerosol inhalation.
Allergic bronchopulmonary aspergillosis (ABPA), which is predominantly a disease of asthmatic subjects, is caused by hypersensitivity to Aspergillus antigens.
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