has the potential to disturb a marine mammal or marine mammal stock in the wild by causing disruption of behavioral patterns, including, but not limited to, migration, breathing, nursing, breeding, feeding, or sheltering.
any act that disturbs or is likely to disturb a marine mammal or marine mammal stock in the wild by causing disruption of natural behavioral patterns, including, but not limited to, migration, surfacing, nursing, breeding, feeding, or sheltering, to a point where such behavioral patterns are abandoned or significantly altered.
It is, therefore, intriguing to speculate that even modest accumulation of radioactivity in the nucleoli, by causing disruption of stress-response co-ordination, could have a disproportionately detrimental effect on cell survival.
Furthermore, TNF α and IFN γ contribute to epithelial barrier damage by causing disruption of tight junctions.
MicroRNAs reduce gene expression by causing disruption of mRNA stability or translation [ 16- 18] and can significantly change cellular processes through both repression of important targets and repression of multiple targets within the same pathway/process [ 19].
Cytochalasin D is a mycotoxin that inhibits both the association and dissociation of actin filament subunits by causing disruption of actin filaments and furthermore the inhibition of actin polymerisation (Goddette and Frieden, 1986).
ERS induced by asbestos caused disruption of calcium homeostasis.
Intrinsic apoptotic signaling, activated by cell damage, is promoted by GSK3 by facilitation of signals that cause disruption of mitochondria and by regulation of transcription factors that control the expression of anti- or pro-apoptotic proteins.
The central neurotoxicity caused by lead is caused by disruption of the intercellular junction that seals the capillary endothelium.
Intracranial hypertension in ALF is caused by the swelling of brain cells, particularly astrocytes [ 14], as a consequence of the accumulation of toxic metabolites that have not been cleared by the liver, and by cerebral hyperemia, caused by disruption of the autoregulation of cerebral blood flow [ 15].
The low contribution of ESCs to chimera formation could have been caused by disruption of the Cdx2 gene which was reported to play an important role in development27,28.
