Sentence examples for by causing defects in from inspiring English sources

Mutations in genes encoding neuronal ion channels have been linked to genetic epilepsies and presumably cause deleterious outcomes in patients by causing defects in ion channel gating that disrupt cellular and network function [7].

The waaL15 mutation increases vancomycin resistance in strains carrying bamB or bamE null mutations that disrupt the OM barrier by causing defects in β-barrel protein assembly (Ricci and Silhavy, 2012).

A significant number of cancers are caused by defects in p21 causing functional defects in p21 or p53 tumour-suppressor proteins.

Diabetes mellitus (DM) is characterized by chronic hyperglycaemia caused by defects in insulin secretion, insulin action, or both, resulting in impaired function in carbohydrate, lipid, and protein metabolism.

Some kidney diseases have overlapping histopathologic features despite being caused by defects in different genes.

There are many diseases associated with defective epithelia and they are often caused by defects in individual cell types.

"If this judge is right, condominium owners are going to have basically unlimited exposure to personal liability for injuries caused by defects in common areas.

Many studies have indicated that most cases of human Laron syndrome are caused by defects in GHR.

Although some 5percentt of cases of the disease are caused by defects in single genes, which are relatively easy to find, the most common kind of Type 2 diabetes is thought to be caused by several contributing genes.

Nagata, S. Autoimmune diseases caused by defects in clearing dead cells and nuclei expelled from erythroid precursors.

A small fraction of these disorders are caused by defects in a single gene.