Ionizing radiation such as that created by radioactive decay or in cosmic rays causes breaks in DNA strands.
It seems that, although chromosome 2 may generally be affected by gains in lung tumours, asbestos may cause breaks in the chromosome and thus result in additional alterations, such as losses.
AESS did not cause breaks in DNA, as shown by the comet assay.
More recently, O3 exposure was found to induce mild and moderate respiratory response among children in Taipei by causing DNA breaks and impairing pulmonary cells (Cheng et al. 2003).
Oxidative stress is known to affect telomere length in proliferating mammalian cells (von Zglinicki, 2002; Serra et al., 2003), probably by causing single-strand breaks in telomeric DNA (von Zglinicki et al., 2000).
Rhegmatogenous retinal detachment (RRD), which refers to detachment of the sensory retina from the retinal pigment epithelium caused by breaks in the retina, is an important cause of permanent visual loss [ 1].
The Cas9 protein, a type II CRISPR-associated Cas, exerts an endonuclease function by causing double-strand breaks (DSBs) in DNA.
These compounds are generally activated by reduction in hypoxic conditions and work in a similar way to oxygen by causing DNA double strand breaks in the presence of irradiation as a result of the fixation of free radical damage (Katz et al. [2009]).
Defense lawyers said that federal prosecutors had overreached in the charges because of the embarrassment caused by the break-in, in which the protesters hung banners, strung crime-scene tape and hammered off a small chunk of the fortresslike Highly Enriched Uranium Materials Facility.
In fact, conventional cancer therapy kills cancer cells by causing irreparable double-strand breaks.
