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This study proposed that genistein acted by causing a reversion of the epithelial to mesenchymal transition, or EMT.
Another possibility is that upregulation of PSG9 might favour tumour development by causing a reversion of the monolayered adult colonic epithelium to an embryonic multilayered arrangement.
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Devernalization can be brought about by exposing previously vernalized plants or seeds to high temperatures, causing a reversion to the original nonflowering condition.
Evidence also showed that second-site replacement of F261 by alanine caused a reversion of the loss-of-function G121 mutant phenotypes, which is consistent with the interpretation that G121 and F261 may interact to form part of the retinal-binding pocket [34].
Therefore, the transient increase in auxin levels imposed by the exogenous treatment caused a reversion by counterbalancing the developmental control exerted by ethylene, thus leading the berry back to the pre-véraison stage with a consequent delay of the ripening progression.
In this study, genistein caused a reversion of this EMT phenotype by increasing levels of E-cadherin, a membrane protein that is associated with increased cell cell adhesion and reduced invasive potential.
Such a link can cause a reversion of observed dependencies of height:diameter ratios on density (Wonn and O'Hara, 2001).
Spraying exogenous GAs can cause a reversion from the adult to the juvenile vegetative phase, producing juvenile traits in newly formed leaves [ 29, 35].
Inhibition of MAPK pathway by UO126, which cause a partial reversion of the transformed phenotype (Figure 3D), induced an increase of Stat3 protein levels in NF861 and NF797 cells, indicating that MAPK activity triggered by TRK oncogenes is involved in the regulation of Stat3 protein levels.
VAPP appears to be caused by a reversion mutation of attenuated virus, thereby converting the virus back to an infectious form that subsequently attacks the nervous system.
Blockade of the EGF receptor inhibited cell proliferation and S6 and ERK phosphorylation, and caused a rapid reversion of phenotype, as determined by HMB45 reactivity.
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